重新展示摘要，突出是数据库

修改建议（Re-write）

为了投中 Database (Oxford)、BMC Plant Biology 或 Horticulture Research，你需要把语气从“生物学发现”转变为“生物信息学工程”。

Title (题目)

目前的题目：

• ArGD: An Integrated Database and Analysis Platform for Artocarpus Genomics and Transcriptomics
• 评价： 中规中矩，还可以。
• 建议微调（增加一点“权威感”）：
  • ArGD: A Comprehensive Multi-omics Hub for Functional Genomics and Breeding in the Genus Artocarpus
  • （用 Hub 或 Resource 显得更像是一个中心化的基础设施，而不仅是一个 Platform）

Abstract (摘要精修版)

我重新帮你写了一版。请注意这一版是如何规避“需要实验”的坑，并**强调“工具属性”**的。

Revised Abstract:

[Background] The genus Artocarpus encompasses ~70 species, including economically significant crops like jackfruit and breadfruit, which are vital for tropical food security and timber. However, breeding for climate resilience is currently hindered by the fragmentation of genomic resources and the lack of a centralized data repository. [The "Product" - 强调系统构建] To bridge this gap, we constructed the Artocarpus Genome Database (ArGD), a comprehensive multi-omics hub designed to facilitate data-driven breeding. Unlike scattered datasets, ArGD systematically integrates and standardizes high-quality genome assemblies from seven Artocarpus species, coupled with extensive transcriptomic datasets across various tissues and stress conditions. [Technical Features - 强调功能而非结果] Beyond basic data retrieval, ArGD features a suite of advanced visualization and analysis modules, including JBrowse for structural variation viewing, interactive synteny blocks for evolutionary analysis, and dynamic expression profiling (heatmaps/volcano plots). [The "Case Study" framing - 这是一个功能，不是一个发现] Distinct from general databases, ArGD incorporates specialized "Gene Family Analysis Modules". These tailored workflows allow users to efficiently explore complex secondary metabolism-related families—such as TPS, ADH, and BAHD—providing rapid insights into fruit quality formation and stress defense without requiring local computational resources. [Conclusion] By offering a user-friendly interface for comparative genomics and functional mining, ArGD serves as a robust community resource that significantly accelerates the identification of molecular markers and supports molecular breeding in Artocarpus.

3. 修改前 vs. 修改后 对比

维度
你的原版 (易被拒)
修改版 (安全)

核心动词
Identify (识别), Find (发现)
Integrate (整合), Facilitate (促进), Enable (赋能)

关于基因家族
"Identifying ADH/TPS families" (我们在做识别)
"Specialized modules for analyzing ADH/TPS" (我们提供识别的工具)

关于目的
Gene discovery (基因发现)
Accelerating research / Community resource (加速研究/社区资源)

给编辑的感觉
一篇生信分析报告，顺便做了个网。
一个精心搭建的科研基础设施/平台。

Section: Technical Advances in Plant Science (植物科学技术进步)

• 为什么选这个？
  • 定位： 这个板块专门发表新的**方法（Methods）、工具（Tools）、软件（Software）、数据库（Databases）**以及实验方案。
  • 审稿逻辑： 这个板块的编辑看重的是：“这个工具好不好用？有没有创新？能不能解决大家的问题？”
  • 对 Case Study 的态度： 在“Technical Advances”板块，你的 Case Study 会被视为 “Demonstration of Utility”（实用性演示）——这是加分项。
  • 对比： 在你原本投的“Functional Genomics”板块，Case Study 被视为 “Preliminary Result without Validation”（未经验证的初步结果）——这是拒稿项。

3. 操作建议

如果你想挽回这篇稿子在 Frontiers 的命运，请按以下步骤操作：

步骤 A：修改 Cover Letter 和 投稿声明

你需要明确告诉编辑，你之前选错了板块，现在申请转到正确的板块。

"We previously submitted this manuscript to the 'Functional and Applied Plant Genomics' section and were rejected due to a lack of wet-lab validation. However, we believe this was a mismatch in section selection. Our manuscript describes a community resource/database (ArGD), not a hypothesis-driven functional study. Therefore, we represent this work for consideration in the section 'Technical Advances in Plant Science', where the focus is on methodologies and resources. We have demonstrated the utility of this resource through a comprehensive case study."

• "We identified 50 TPS genes. Heatmap analysis showed that gene A is highly expressed, indicating it plays a role in aroma." (审稿人OS：你说它 play a role 就 play a role？证据呢？去做个 PCR！)
• ✅ 正确的写法 (像工具演示): "Using the 'Family' identification module in ArGD, we successfully retrieved 50 TPS gene candidates. The 'Expression' module visualized their patterns, suggesting potential candidates for future breeding. This demonstrates the platform's capability to rapidly filter key genes.